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CS-W001157 4
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3,5-Dimethyladamantan-1-ol

  • CAS No. 707-37-9

  • Cat. No. CS-W016006
  • Purity≥98%
  • MDL No.MFCD00074775

*For research and further manufacturing use only, not for direct human use.

3,5-Dimethyladamantan-1-ol|CS-W016006

Structure of 707-37-9

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General Information

  • CAS No. 707-37-9
  • Cat. No. CS-W016006
  • Purity ≥98%
  • MDL No. MFCD00074775
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀O
  • Molecular Weight 180.29
  • Synonym(s) None
  • SMILES O[C@]1(C2)C[C@]3(C)C[C@@H](C[C@@]2(C)C3)C1

Description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membranebilayers. It has three-carbon backbone of glycerol, two long-chainfatty acids,esterified tohydroxyl groups on carbons 1 and 2 of the glycerol andphosphoric acidesterified to the C3hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1-rac-glycerol) (DOPG)/18:1 (9-Cis) PGhas two hydroxyl groups in its head group. It is an anionic lipid.18:1 (9-Cis) PG has been used:in the preparation of giant unilamellar vesicle (GUV)in the preparation 200 nm large unilamellar vesicles (LUV)as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge

Application

3,5-Dimethyladamantan-1-ol serves as a robust, sterically encumbered tertiary alcohol scaffold for medicinal chemistry and materials science applications. Its rigid adamantane core imparts exceptional thermal and oxidative stability, while the hydroxyl group enables straightforward derivatization via esterification or ether formation. The molecule exhibits excellent bench stability and facilitates purification by recrystallization or chromatography, making it a practical building block in the synthesis of functionalized cage compounds and chiral auxiliaries.

Synthesis

  • Route1

    References

    • Reddy, Jambula Mukunda; Prasad, Ganji; Raju, Veeramalla; Ravikumar, Mylavarapu; Himabindu, Vurumidi; Reddy, Ghanta Mahesh Organic Process Research and Development, 2007 , vol. 11, # 2 p. 268 - 269
  • Route2
    • In-stock
      1,3-Dimethyladamantane|CS-0152705
      702-79-4
    • ~74%
    • null|null
      33794-98-8
    • In-stock
      3,5-Dimethyladamantan-1-ol|CS-W016006
      707-37-9
    • 5,7-Dimethyladamantane-1,3-diol|CS-0251378
      10347-01-0

    References

    • Tetrahedron Letters, , vol. 40, # 11 p. 2165 - 2168
  • Route3

    References

    • Chemistry - A European Journal, , vol. 10, # 24 p. 6489 - 6496

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.7277
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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