tert-Butyl (tert-butoxycarbonyl)-d-serinate

Name: tert-Butyl (tert-butoxycarbonyl)-d-serinate
Brand: ChemScene
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CAS No. 71630-31-4
Cat. No. CS-0670650
Purity≥98%
MDL No.MFCD29077539

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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tert-Butyl (tert-butoxycarbonyl)-d-serinate|CS-0670650

Structure of 71630-31-4

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Description

tert-Butyl (tert-butoxycarbonyl)-D-serinate features a protected D-serine scaffold with orthogonal reactivity, enabling selective incorporation into peptide sequences. The tert-butoxycarbonyl group ensures stability during synthesis and facilitates straightforward deprotection under mild acidic conditions. This derivative supports efficient access to non-natural amino acid motifs in peptide-based drug discovery and chemical biology applications.

Application

tert-Butyl (tert-butoxycarbonyl)-D-serinate serves as a stable, bench-ready D-amino acid building block for peptide synthesis, enabling selective incorporation of D-serine residues. The Boc group provides excellent protection under standard acidic conditions and facilitates straightforward deprotection during late-stage functionalization. Its compatibility with diverse coupling reagents and tolerance to common functional groups make it a practical choice for constructing bioactive peptides and heterocyclic scaffolds.

General Information

CAS No. 71630-31-4
Cat. No. CS-0670650
Purity ≥98%
MDL No. MFCD29077539
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₃NO₅
Molecular Weight 261.31
Synonym(s) None
SMILES CC(C)(C)OC(=O)[C@@H](CO)NC(=O)OC(C)(C)C

Computational Chemistry Data

TPSA 84.86
LogP 1.2137
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty chain compounds

Life Science Amino Acids and their Derivatives Serine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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tert-Butyl (tert-butoxycarbonyl)-d-serinate

CAS No. 71630-31-4

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