6-Chloro-4-methoxy Nicotinic Acid

Name: 6-Chloro-4-methoxy Nicotinic Acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 716362-10-6
Cat. No. CS-W003725
Purity≥98%
MDL No.MFCD10000638

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloro-4-methoxy Nicotinic Acid|CS-W003725

Structure of 716362-10-6

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Chloro-4-methoxy nicotinic acid is a bench-stable, electron-deficient pyridine derivative featuring a chloro group at the 6-position and a methoxy substituent at the 4-position. This combination enhances regioselectivity in cross-coupling reactions and improves solubility in polar organic solvents. The compound serves as a key building block for pharmaceutical intermediates and bioactive heterocycles.

Application

6-Chloro-4-methoxy nicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted pyridine scaffolds through standard coupling and cyclization reactions. Its orthogonal functional groups—chlorine at C6 and methoxy at C4—facilitate selective derivatization, while its bench-stable crystalline form simplifies handling and purification. This compound functions effectively in Suzuki-Miyaura and Buchwald-Hartwig cross-coupling protocols, supporting efficient access to bioactive heterocycles and API intermediates.

General Information

CAS No. 716362-10-6
Cat. No. CS-W003725
Purity ≥98%
MDL No. MFCD10000638
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClNO₃
Molecular Weight 187.58
Synonym(s) 6-Chloro-4-methoxynicotinic acid
SMILES OC(C1=CN=C(Cl)C=C1OC)=O

Computational Chemistry Data

TPSA 59.42
LogP 1.4418
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

6-Chloro-4-methoxy Nicotinic Acid sigma6-Chloro-4-methoxy Nicotinic Acid manufacturer6-Chloro-4-methoxy Nicotinic Acid price6-Chloro-4-methoxy Nicotinic Acid structure6-Chloro-4-methoxy Nicotinic Acid SDSbuy 6-Chloro-4-methoxy Nicotinic Acid6-Chloro-4-methoxy Nicotinic Acid supplier6-Chloro-4-methoxy Nicotinic Acid uses6-Chloro-4-methoxy Nicotinic Acid molecular weightprice of 6-Chloro-4-methoxy Nicotinic Acid6-Chloro-4-methoxy Nicotinic Acid chemical name formula of 6-Chloro-4-methoxy Nicotinic Acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Chloro-4-methoxy Nicotinic Acid

CAS No. 716362-10-6

Recommended Products