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Structure of 71916-91-1
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2-(Bromomethyl)-4-chloro-1-fluorobenzene features a strategically positioned bromomethyl group flanked by chlorine and fluorine substituents, enabling selective functionalization in late-stage diversification. This electron-deficient aryl halide integrates readily into cross-coupling protocols, offering high reactivity under mild conditions with minimal side reactions.
2-(Bromomethyl)-4-chloro-1-fluorobenzene serves as a versatile aryl building block for transition-metal-catalyzed couplings, enabling efficient construction of biaryl and heterocyclic scaffolds. The bromomethyl group facilitates nucleophilic substitution and cross-coupling reactions, while the ortho-fluoro and para-chloro substituents provide orthogonal reactivity and enhanced stability under standard synthetic conditions. Its bench-stable nature and compatibility with palladium-catalyzed transformations make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: