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Structure of 723283-89-4
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5-Bromoquinolin-4-ol integrates a bromine substituent at the 5-position and a hydroxyl group at the 4-position of the quinoline scaffold, delivering a rigid, electron-deficient heteroaromatic system. This configuration enhances reactivity in palladium-catalyzed cross-coupling processes while maintaining stability under standard handling conditions. The molecule's polarity supports solubility in common organic solvents, enabling seamless incorporation into synthetic workflows for pharmaceutical intermediates and functional materials.
5-Bromoquinolin-4-ol serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality and phenolic hydroxyl group. The molecule exhibits bench stability and facilitates efficient derivatization in late-stage functionalization, particularly in the construction of biologically relevant quinoline scaffolds. Its dual reactivity profile—bromine for coupling and hydroxyl for protection or substitution—supports orthogonal transformations in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: