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Structure of 72411-52-0
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5-(4-Fluorophenyl)-1H-pyrazol-3-amine integrates a fluorinated aryl moiety with a pyrazole scaffold, delivering enhanced electronic modulation and metabolic stability. This bench-stable compound serves as a key building block in targeted kinase inhibitor development and medicinal chemistry campaigns requiring electron-deficient heterocyclic systems.
5-(4-Fluorophenyl)-1H-pyrazol-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-based scaffolds through standard coupling and functionalization reactions. Its fluorinated aryl group enhances metabolic stability and modulates electronic properties, while the primary amine facilitates derivatization via acylation, alkylation, or cross-coupling. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis campaigns in drug discovery.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: