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CS-W001157 4
Total: USD 88.00

β-Pyrrolidinoethyl chloride Hydrochloride

  • CAS No. 7250-67-1

  • Cat. No. CS-D1148
  • Molecule weight170.08
  • Purity≥95%
  • MDL No.MFCD00012718

*For research and further manufacturing use only, not for direct human use.

β-Pyrrolidinoethyl chloride Hydrochloride|CS-D1148

Structure of 7250-67-1

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General Information

  • CAS No. 7250-67-1
  • Cat. No. CS-D1148
  • Purity ≥95%
  • MDL No. MFCD00012718
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃Cl₂N
  • Molecular Weight 170.08
  • Synonym(s) Pyrrolidine, 1-(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI); 1-(2-Chloroethyl)pyrrolidine hydrochloride; N-Chloroethylpyrprolidine HCl
  • SMILES ClCCN1CCCC1.Cl

Description

1-(2-Chloroethyl)pyrrolidine hydrochloride features a reactive chloroethyl group enabling efficient alkylation under mild conditions. This bench-stable, moisture-tolerant compound integrates readily into synthetic pathways for bioactive heterocycles and pharmaceutical intermediates. The pyrrolidine core enhances solubility and facilitates downstream functionalization.

Application

1-(2-Chloroethyl)pyrrolidine hydrochloride serves as a versatile alkylating agent in synthetic organic chemistry, enabling efficient introduction of pyrrolidinyl motifs into target molecules. Its bench-stable form facilitates handling and purification, while the chloroethyl group exhibits high reactivity toward nucleophiles under mild conditions. This compound functions effectively in the construction of bioactive heterocyclic scaffolds and is widely employed in medicinal chemistry for targeted functionalization.

Synthesis

  • Route1
    • null|null
      123-75-1
    • null|null
      107-07-3
    • ~61%
    • In-stock
      β-Pyrrolidinoethyl chloride Hydrochloride|CS-D1148
      7250-67-1

    References

    • CHINA PHARMACEUTICAL UNIVERSITY; Xiang, Hua; Wang, Tianlin; Xiao, Hong; You, Qidong; Yao, Yao; Li, Xiaobo; Liao, Qingjiang Patent: US2013/85140 A1, 2013 ; Location in patent: Paragraph 0068; 0069 ;
  • Route2

    References

    • BAYER PHARMACEUTICALS CORPORATION Patent: WO2007/56170 A2, 2007 ; Location in patent: Page/Page column 108 ; WO 2007/056170 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   1.7428
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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