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Structure of 72587-15-6
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2-Chloro-3-nitro-5-(trifluoromethyl)pyridine features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the chloro and nitro substituents enable selective cross-coupling and functionalization under mild conditions. This pyridine derivative serves as a key intermediate in the synthesis of bioactive heterocycles and pharmaceutical candidates.
2-Chloro-3-nitro-5-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling late-stage functionalization via palladium-catalyzed cross-coupling. Its trifluoromethyl and nitro groups enhance electron-withdrawing character, facilitating nucleophilic substitution at the C2 position. The molecule exhibits good bench stability and compatibility with common protecting group strategies, supporting efficient synthesis of heterocyclic scaffolds relevant to agrochemical and pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: