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Structure of 72700-48-2
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4-Chloropteridine features a chlorine atom at the C4 position of the pteridine core, enhancing its electron-deficient character and reactivity in transition metal-catalyzed coupling processes. This substitution improves stability under standard conditions while maintaining compatibility with synthetic transformations requiring precise heterocyclic control.
4-Chloropteridine serves as a key intermediate in the synthesis of pteridine-based scaffolds, enabling direct functionalization at the C4 position. Its chlorine substituent facilitates palladium-catalyzed cross-coupling reactions and nucleophilic substitution pathways under mild conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it a practical building block for medicinal chemistry campaigns targeting folate analogs and enzyme inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: