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Structure of 7298-67-1
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N-(3-Acetyl-4-hydroxyphenyl)acetamide features a phenolic hydroxyl group flanked by an acetyl and acetamide substituent, offering enhanced solubility and stability in aqueous and organic media. This scaffold integrates readily into bioactive molecule synthesis, particularly for kinase inhibitors and anti-inflammatory agents. The para-positioned hydroxyl enables hydrogen bonding, while the acetyl moiety provides metabolic resistance.
N-(3-Acetyl-4-hydroxyphenyl)acetamide serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive phenolic scaffolds. The acetyl and hydroxyl groups provide orthogonal functional handles for selective derivatization, while the amide linkage ensures stability under standard synthetic conditions. Its bench-stable nature and compatibility with common coupling and protection strategies facilitate streamlined synthesis of complex heterocycles and drug candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: