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Structure of 73027-79-9
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4,6-Dichloronicotinic acid features a pyridine ring bearing two chlorine substituents at the 4- and 6-positions, delivering enhanced electron-withdrawing character. This configuration supports efficient coupling reactions and facilitates incorporation into bioactive scaffolds requiring halogenated heterocyclic motifs. The compound exhibits bench-stable handling and compatibility with standard synthetic protocols.
4,6-Dichloronicotinic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to functionalized heterocycles via standard coupling reactions. Its ortho-dichloro substitution pattern facilitates directed metalation and palladium-catalyzed cross-coupling, while the carboxylic acid group supports direct derivatization or salt formation for improved solubility and purification. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it a reliable scaffold for API development and process optimization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: