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Structure of 27684-84-0
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5-Bromo-2-nitrophenol features a bromine substituent at the 5-position and a nitro group at the 2-position on a phenolic scaffold. This electron-deficient aromatic system enables direct functionalization in cross-coupling reactions, while the phenolic hydroxyl offers a handle for derivatization. The compound exhibits enhanced stability under standard bench conditions and serves as a key intermediate in synthetic pathways requiring halogenated nitroaromatics.
5-Bromo-2-nitrophenol serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization via palladium-catalyzed cross-coupling reactions. Its ortho-nitro and bromo substituents offer complementary reactivity for sequential transformations, including nitro group reduction followed by coupling or cyclization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: