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Structure of 731002-50-9
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3-Hydroxy-4-(trifluoromethyl)benzonitrile features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the hydroxyl moiety enables hydrogen bonding and further functionalization. This combination delivers enhanced solubility and reactivity in synthetic intermediates for pharmaceutical and agrochemical development under standard conditions.
3-Hydroxy-4-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and functionalized aryl scaffolds. Its ortho-hydroxynitrile motif offers compatibility with standard coupling reactions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: