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Structure of 7311-64-0
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3-Bromothiophene-2-carboxylic acid delivers a brominated thiophene scaffold with a carboxylic acid handle, enabling direct coupling in cross-coupling and functionalization workflows. The electron-deficient ring facilitates palladium-catalyzed transformations, while the acidic proton supports derivatization under mild conditions. This bench-stable reagent integrates seamlessly into synthetic sequences requiring halogenated heterocycles.
3-Bromothiophene-2-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates derivatization via amide formation, esterification, or decarboxylative functionalization. The compound exhibits good bench stability and is compatible with standard synthetic workflows, enabling efficient access to substituted thiophene scaffolds relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317
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Precautionary Statements : P261-P272-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: