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Structure of 7312-18-7
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5-Bromobenzo[b]thiophene-2-carbaldehyde features a brominated benzo[b]thiophene core with an aldehyde at the 2-position, enabling direct functionalization in cross-coupling and heterocyclic synthesis. The electron-deficient aromatic system enhances reactivity in palladium-catalyzed transformations, while the aldehyde group provides a handle for derivatization under mild conditions. This compound serves as a key building block for advanced materials and bioactive molecule scaffolds.
5-Bromobenzo[b]thiophene-2-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions and electrophilic functionalization at the thiophene core. The aldehyde group facilitates direct derivatization via Wittig, reductive amination, or Grignard addition, while the bromine substituent supports further diversification through Suzuki-Miyaura or Stille coupling. Bench-stable and readily purified by flash chromatography, it functions effectively in the construction of complex pharmaceutical scaffolds and advanced materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P264-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: