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tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate

  • CAS No. 73470-46-9

  • Cat. No. CS-0154460
  • Molecule weight202.25
  • Purity≥95%
  • MDL No.MFCD21104138

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate|CS-0154460

Structure of 73470-46-9

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General Information

  • CAS No. 73470-46-9
  • Cat. No. CS-0154460
  • Purity ≥95%
  • MDL No. MFCD21104138
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O₃
  • Molecular Weight 202.25
  • Synonym(s) Carbamic acid, (2-amino-1,1-dimethyl-2-oxoethyl)-, 1,1-dimethylethylester
  • SMILES CC(C)(OC(NC(C)(C(N)=O)C)=O)C

Synthesis

  • Route1

    References

    • F. HOFFMANN-LA ROCHE AG; BISSANTZ, Caterina; GRETHER, Uwe; HEBEISEN, Paul; KIMBARA, Atsushi; LIU, Qingping; NETTEKOVEN, Matthias; PRUNOTTO, Marco; ROEVER, Stephan; ROGERS-EVANS, Mark; SCHULZ-GASCH, Tanja; ULLMER, Christoph; WANG, Zhiwei; YANG, Wulun Patent: WO2012/168350 A1, 2012 ; Location in patent: Page/Page column 80 ; WO 2012/168350 A1
  • Route2

    References

    • GLAXO GROUP LIMITED Patent: WO2008/17691 A1, 2008 ; Location in patent: Page/Page column 24 ; WO 2008/017691 A1
  • Route3

    References

    • Rodrigues, Ligia M.; Fonseca, Jose I.; Maia, Hernani L.S. Tetrahedron, 2004 , vol. 60, # 40 p. 8929 - 8936

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   81.42
  • LogP   0.775
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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