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Structure of 73831-13-7
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4-Cyano-3-methylbenzoic acid features a conjugated system integrating an electron-deficient nitrile group and a methyl-substituted aromatic ring, enabling robust coupling in amide bond formation. This bench-stable carboxylic acid delivers high reactivity under standard conditions, facilitating efficient synthesis of bioactive esters and pharmaceutical intermediates.
4-Cyano-3-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling direct access to substituted benzimidazoles and other heterocyclic scaffolds via standard condensation protocols. Its orthogonal functional groups—cyano, methyl, and carboxylic acid—support diverse downstream transformations, including amidation, esterification, and metal-catalyzed cross-couplings. The compound exhibits excellent bench stability and facilitates straightforward purification by recrystallization or column chromatography, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: