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Structure of 7396-28-3
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3-(3-Chlorophenyl)prop-2-ynoic acid features a conjugated alkyne-carboxylic acid system linked to a chlorinated phenyl ring, enabling efficient coupling in click chemistry and transition-metal-catalyzed transformations. The electron-withdrawing chlorine substituent enhances reactivity while maintaining bench-stable handling under standard conditions.
3-(3-Chlorophenyl)prop-2-ynoic acid serves as a versatile building block for alkyne-based conjugate additions and Sonogashira coupling reactions. Its terminal alkyne functionality enables efficient C–C bond formation under palladium catalysis, while the ortho-chlorinated aryl group offers compatibility with cross-coupling and electrophilic functionalization. The carboxylic acid moiety facilitates direct derivatization or activation for amide and ester synthesis, enhancing utility in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: