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CS-W001157 4
Total: USD 88.00

L-Arginine

  • CAS No. 74-79-3

  • Cat. No. CS-2045
  • Purity≥98%
  • MDL No.MFCD00002635

*For research and further manufacturing use only, not for direct human use.

L-Arginine|CS-2045

Structure of 74-79-3

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General Information

  • CAS No. 74-79-3
  • Cat. No. CS-2045
  • Purity ≥98%
  • MDL No. MFCD00002635
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄N₄O₂
  • Molecular Weight 174.20
  • Synonym(s) None
  • SMILES N[C@@H](CCCNC(N)=N)C(O)=O

Description

L-Arginine is a semi-essential amino acid featuring a guanidino group that confers strong basicity and hydrogen-bonding capacity. This polar side chain enhances solubility in aqueous environments and supports roles in nitric oxide synthesis, urea cycle metabolism, and protein stability. Its presence in enzymatic active sites underscores functional relevance in catalytic processes.

Application

L-Arginine serves as a vital building block in peptide synthesis and metabolic pathway studies, functioning as a key precursor for nitric oxide and urea cycle intermediates. Its guanidino side chain enables robust hydrogen bonding and charge stabilization in biological systems, while its bench-stable crystalline form facilitates handling and purification. Widely used in biochemical assays and cell culture media, L-Arginine supports endothelial function and protein engineering workflows with consistent performance across standard synthetic and biological applications.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 102, # 15 p. 5115 - 5117
  • Route2

    References

    • Chen, Chun-Chi; Rajagopal, Basker; Liu, Xuan Yu; Chen, Kuan Lin; Tyan, Yu-Chang; Lin, Fui; Lin, Po-Chiao Amino Acids, 2014 , vol. 46, # 2 p. 367 - 374
  • Route3
    • null|null
      1432516-48-7
    • ~%
    • In-stock
      L-Lys-OH Amino acid impurity|CS-1733140
      56-87-1
    • In-stock
      L-Arginine|CS-2045
      74-79-3
    • L-Phenylalanine Aspartame Impurity|CS-0229723
      63-91-2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 10 p. 2968 - 2973

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   125.22
  • LogP   -1.33843
  • H_Acceptors   3
  • H_Donors   5
  • Rotatable_Bonds   5

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