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Structure of 74090-48-5
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This bench-stable phenolic alcohol features a methoxy group at the ortho position and a methyl substituent at the meta position, enhancing electronic delocalization and steric protection. The benzylic hydroxyl enables straightforward derivatization, while the substituted aromatic core supports selective functionalization in synthesis.
(2-Methoxy-3-methylphenyl)methanol serves as a versatile arylmethanol building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxy and methyl substituents provide favorable electronic and steric profiles, enabling selective functionalization in palladium-catalyzed cross-coupling reactions. The benzylic alcohol functionality facilitates oxidation to aldehydes or carboxylic acids, and the molecule exhibits good bench stability and ease of purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: