3-Chloro-L-tyrosine

Name: 3-Chloro-L-tyrosine
Brand: ChemScene
Availability: InStock
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CAS No. 7423-93-0
Cat. No. CS-W021911
Purity≥95%
MDL No.MFCD00045865

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 7423-93-0

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Description

3-Chloro-L-tyrosine is a halogenated analog of L-tyrosine featuring a chlorine atom at the meta position of the aromatic ring. This substitution enhances electron deficiency while maintaining compatibility with enzymatic incorporation pathways. The compound serves as a valuable tool for probing protein structure-function relationships and integrating site-specific halogen handles into peptide architectures under standard biological conditions.

Application

3-Chloro-L-tyrosine serves as a bioisosteric analog of L-tyrosine, enabling the incorporation of a halogenated aromatic moiety into peptides and peptidomimetics. Its chlorine substituent enhances metabolic stability and modulates electronic properties without compromising solubility or synthetic tractability. The compound functions reliably in solid-phase peptide synthesis, offering improved pharmacokinetic profiles in targeted therapeutic candidates.

General Information

CAS No. 7423-93-0
Cat. No. CS-W021911
Purity ≥95%
MDL No. MFCD00045865
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀ClNO₃
Molecular Weight None
Synonym(s) 3-Chlorotyrosine
SMILES O=C(O)[C@@H](N)CC1=CC=C(O)C(Cl)=C1

Computational Chemistry Data

TPSA 83.55
LogP 1
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Natural Products

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids non-Proteinogenic Amino Acids

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3-Chloro-L-tyrosine

CAS No. 7423-93-0

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