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CS-W001157 4
Total: USD 88.00

ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate

  • CAS No. 74476-53-2

  • Cat. No. CS-0455448
  • Molecule weight282.75
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate|CS-0455448

Structure of 74476-53-2

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General Information

  • CAS No. 74476-53-2
  • Cat. No. CS-0455448
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₁ClN₂O₂S
  • Molecular Weight 282.75
  • Synonym(s) Ethyl 2-amino-4-(4-chlorophenyl)-1,3-thiazole-5-carboxylate
  • SMILES O=C(OCC)C=1SC(=NC1C2=CC=C(Cl)C=C2)N

Synthesis

  • Route1

    References

    • Monsanto Company Patent: US4308391 A1, 1981 ;
  • Route2
    • null|null
      24045-75-8
    • null|null
      17356-08-0
    • ~97%
    • ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate|CS-0455448
      74476-53-2

    References

    • Lethu, Sebastien; Ginisty, Maryon; Bosc, Damien; Dubois, Joelle Journal of Medicinal Chemistry, 2009 , vol. 52, # 20 p. 6205 - 6208
  • Route3
    • null|null
      122-01-0
    • ~%
    • ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate|CS-0455448
      74476-53-2

    References

    • Journal of Heterocyclic Chemistry, , vol. 22, p. 1621 - 1630

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.21
  • LogP   3.2224
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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