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Structure of 7450-63-7
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Dimethyl (methylenebis(4,1-phenylene))dicarbamate features a rigid bisaryl backbone with dual carbamate ester groups, enabling efficient incorporation into peptide mimetics and bioactive scaffolds. The methylene bridge imparts conformational stability, while the terminal carbamates offer tunable reactivity for late-stage functionalization in synthetic medicinal chemistry workflows.
Dimethyl (methylenebis(4,1-phenylene))dicarbamate serves as a stable, bench-ready diol protecting group precursor, enabling selective protection of vicinal diols under mild conditions. Its rigid aromatic backbone provides excellent regioselectivity in cyclic carbonate formation and functions effectively in the synthesis of complex heterocyclic scaffolds. The molecule exhibits high functional group tolerance and facilitates straightforward purification via crystallization or flash chromatography, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H400-H410
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Precautionary Statements : P273-P391-P501
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Lot numbers can be found on the outside label of a product: