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CS-W001157 4
Total: USD 88.00

(R)-3-Phenylmorpholine

  • CAS No. 74572-03-5

  • Cat. No. CS-W021137
  • Purity≥95%
  • MDL No.MFCD11016233

*For research and further manufacturing use only, not for direct human use.

(R)-3-Phenylmorpholine|CS-W021137

Structure of 74572-03-5

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General Information

  • CAS No. 74572-03-5
  • Cat. No. CS-W021137
  • Purity ≥95%
  • MDL No. MFCD11016233
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO
  • Molecular Weight 163.22
  • Synonym(s) (3R)-3-phenylmorpholine
  • SMILES [C@H]1(C2=CC=CC=C2)NCCOC1

Description

(R)-3-Phenylmorpholine is a chiral morpholine derivative featuring a phenyl group at the 3-position, offering enhanced stereochemical control in asymmetric synthesis. This bench-stable compound integrates readily into medicinal chemistry campaigns, providing a rigid, electron-rich scaffold for ligand development and target-directed optimization.

Application

(R)-3-Phenylmorpholine serves as a valuable chiral building block in medicinal chemistry, enabling the construction of diverse heterocyclic scaffolds. Its phenyl-substituted morpholine core exhibits favorable bench stability and functional group tolerance, facilitating downstream transformations such as Suzuki-Miyaura coupling and amide formation. The stereochemistry at the 3-position is configurationally stable under standard reaction conditions, making it well-suited for asymmetric synthesis and target-oriented drug discovery workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.3475
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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