(R)-3-Phenylmorpholine

Name: (R)-3-Phenylmorpholine
Brand: ChemScene
Availability: InStock
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CAS No. 74572-03-5
Cat. No. CS-W021137
Purity≥95%
MDL No.MFCD11016233

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

(R)-3-Phenylmorpholine is a chiral morpholine derivative featuring a phenyl group at the 3-position, offering enhanced stereochemical control in asymmetric synthesis. This bench-stable compound integrates readily into medicinal chemistry campaigns, providing a rigid, electron-rich scaffold for ligand development and target-directed optimization.

Application

(R)-3-Phenylmorpholine serves as a valuable chiral building block in medicinal chemistry, enabling the construction of diverse heterocyclic scaffolds. Its phenyl-substituted morpholine core exhibits favorable bench stability and functional group tolerance, facilitating downstream transformations such as Suzuki-Miyaura coupling and amide formation. The stereochemistry at the 3-position is configurationally stable under standard reaction conditions, making it well-suited for asymmetric synthesis and target-oriented drug discovery workflows.

General Information

CAS No. 74572-03-5
Cat. No. CS-W021137
Purity ≥95%
MDL No. MFCD11016233
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃NO
Molecular Weight 163.22
Synonym(s) (3R)-3-phenylmorpholine
SMILES [C@H]1(C2=CC=CC=C2)NCCOC1

Computational Chemistry Data

TPSA 21.26
LogP 1.3475
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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(R)-3-Phenylmorpholine

CAS No. 74572-03-5

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