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Structure of 745784-04-7
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3,5-Difluoropicolinic acid is a bench-stable, electron-deficient heteroaromatic carboxylic acid featuring fluorine substituents at the 3- and 5-positions of the pyridine ring. This strategic substitution enhances its utility in medicinal chemistry and materials science, where controlled reactivity and metabolic stability are critical.
3,5-Difluoropicolinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds common in pharmaceutical development. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates direct coupling reactions or derivatization. Bench-stable and compatible with standard synthetic protocols, it functions effectively in peptide coupling, amide formation, and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: