Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl piperidine-4-carboxylate hydrochloride

  • CAS No. 7462-86-4

  • Cat. No. CS-W002947
  • Purity≥98%
  • MDL No.MFCD02667641

*For research and further manufacturing use only, not for direct human use.

Methyl piperidine-4-carboxylate hydrochloride|CS-W002947

Structure of 7462-86-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 7462-86-4
  • Cat. No. CS-W002947
  • Purity ≥98%
  • MDL No. MFCD02667641
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.65
  • Synonym(s) METHYL ISONIPECOTINATE HYDROCHLORIDE
  • SMILES COC(=O)C1CCNCC1.Cl

Description

Methyl piperidine-4-carboxylate hydrochloride is a bench-stable, moisture-tolerant heterocyclic ester featuring a protonated piperidine nitrogen. This salt form enhances solubility in polar solvents and facilitates downstream functionalization in synthetic routes. The methyl ester group enables selective derivatization, while the charged piperidine moiety supports efficient coupling reactions in medicinal chemistry applications.

Application

Methyl piperidine-4-carboxylate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles. Its bench-stable, crystalline form facilitates handling and purification, while the protected amine and ester functionalities offer orthogonal reactivity for late-stage diversification. Functions as a key intermediate in the synthesis of piperidine-based pharmaceuticals and functionalized scaffolds via standard coupling, reduction, and cyclization protocols.

Synthesis

  • Route1
    • null|null
      67-56-1
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • ~85%
    • Methyl piperidine-4-carboxylate hydrochloride|CS-W002947
      7462-86-4

    References

    • Alfaro-Lopez, Josue; Okayama, Toru; Hosohata, Keiko; Davis, Peg; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J. Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5359 - 5368
  • Route2
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • ~%
    • Methyl piperidine-4-carboxylate hydrochloride|CS-W002947
      7462-86-4

    References

    • US6069143 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.5808
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 7462-86-4 sigma7462-86-4 manufacturer7462-86-4 price7462-86-4 structure7462-86-4 SDSbuy 7462-86-47462-86-4 supplier7462-86-4 uses7462-86-4 molecular weightprice of 7462-86-47462-86-4 chemical name formula of 7462-86-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label