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Structure of 747413-21-4
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1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine delivers a boronate ester handle for efficient Suzuki-Miyaura cross-coupling. The tetramethyl-substituted dioxaborolane moiety ensures high stability and moisture tolerance, enabling reliable use under standard conditions. This piperazine derivative integrates seamlessly into complex molecular architectures, particularly in pharmaceutical and materials science applications requiring robust functional group compatibility.
1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate moiety enables reliable coupling with aryl halides under mild conditions, offering excellent functional group tolerance and bench stability. Its piperazine core provides structural diversity for medicinal chemistry applications, while the methylated nitrogen enhances solubility and metabolic stability. This reagent facilitates efficient construction of complex biaryl scaffolds common in pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: