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Structure of 74788-45-7
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1-(3-Fluorophenyl)ethanamine is a bench-stable, moisture-tolerant amine featuring a para-fluorinated phenyl ring that enhances metabolic stability. This electron-deficient aryl moiety integrates readily into bioactive scaffolds, enabling efficient coupling in late-stage functionalization and pharmaceutical synthesis workflows.
1-(3-Fluorophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amine functionalization. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, while the pendant ethylamine side chain facilitates conjugation via amide coupling, reductive amination, or alkylation. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multistep syntheses of pharmaceutical intermediates and CNS-targeted compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317-H319
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Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501
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Lot numbers can be found on the outside label of a product: