(S)-3-Ethylmorpholine

Name: (S)-3-Ethylmorpholine
Brand: ChemScene
Availability: InStock
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CAS No. 748117-01-3
Cat. No. CS-0146945
Purity≥96%
MDL No.MFCD11519097

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 748117-01-3

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Description

(S)-3-Ethylmorpholine is a chiral heterocyclic amine featuring a stereodefined nitrogen atom within a morpholine core. This bench-stable compound integrates readily into asymmetric synthesis, serving as a selective ligand or auxiliary in catalytic transformations. Its ethyl substitution enhances solubility and modulates basicity, enabling efficient coupling with electrophiles under mild conditions.

Application

(S)-3-Ethylmorpholine serves as a versatile chiral building block in medicinal chemistry, enabling stereoselective synthesis of bioactive molecules. Its morpholine core exhibits favorable solubility and metabolic stability, while the (S)-configuration provides defined stereochemical control in target-oriented synthesis. The ethyl substituent enhances lipophilicity and modulates electronic properties, facilitating efficient coupling reactions and functional group interconversions. This compound demonstrates excellent bench stability and ease of purification, making it well-suited for scalable applications in API development and process chemistry workflows.

General Information

CAS No. 748117-01-3
Cat. No. CS-0146945
Purity ≥96%
MDL No. MFCD11519097
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO
Molecular Weight 115.17
Synonym(s) morpholine, 3-ethyl-, (3S)-
SMILES CC[C@@H]1NCCOC1

Computational Chemistry Data

TPSA 21.26
LogP 0.3848
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-3-Ethylmorpholine

CAS No. 748117-01-3

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