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Structure of 74844-99-8
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3-Methylquinolin-2-amine features a quinoline scaffold with a methyl group at the 3-position and an amino functionality at the 2-position, delivering enhanced electron density and improved solubility in polar solvents. This structural configuration supports efficient integration into pharmaceutical intermediates and ligand design, particularly in metal-catalyzed coupling reactions where steric and electronic modulation are critical.
3-Methylquinolin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through standard functional group transformations. Its inherent stability and compatibility with palladium-catalyzed cross-coupling reactions facilitate the construction of complex heterocycles. The molecule functions effectively as a nitrogen donor in transition metal catalysis and supports direct arylation or alkylation protocols, offering practical utility in synthetic routes to bioactive compounds.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: