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Structure of 7499-07-2
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4-Chloro-2-methylbenzoic acid features a strategically positioned chloro group and methyl substituent on the benzene ring, delivering enhanced electron-withdrawing character and improved solubility in organic solvents. This structural arrangement facilitates direct incorporation into pharmaceutical intermediates and agrochemical scaffolds via standard coupling reactions under mild conditions.
4-Chloro-2-methylbenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of a chlorinated aromatic core with orthogonal functional handles. Its carboxylic acid group facilitates amide coupling, esterification, and metal-catalyzed transformations, while the ortho-methyl and para-chloro substituents provide steric and electronic modulation. The compound exhibits excellent bench stability and ease of purification, supporting reliable use in multi-step syntheses and scale-up processes.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P280-P501
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Lot numbers can be found on the outside label of a product: