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Structure of 7584-08-9
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3,5-Dimethylisonicotinonitrile features a pyridine core with methyl groups at the 3- and 5-positions and a nitrile group at the 2-position, delivering enhanced electron-withdrawing character and steric protection. This configuration enables robust performance in cross-coupling reactions and transition metal catalysis, particularly under ambient conditions. The molecule exhibits high thermal stability and excellent solubility in common organic solvents, facilitating straightforward handling in synthetic workflows.
3,5-Dimethylisonicotinonitrile serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling the construction of functionalized heterocyclic scaffolds. Its pyridine core with ortho- and meta-directing nitrile and methyl groups facilitates regioselective transformations, including palladium-catalyzed couplings and nucleophilic additions. The compound exhibits excellent bench stability and is readily purified by column chromatography, making it well-suited for multi-step synthesis workflows.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P304+P340-P330-P362-P405
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Lot numbers can be found on the outside label of a product: