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Structure of 891785-28-7
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6-Bromoisoquinolin-3-amine features a brominated isoquinoline core with a strategically positioned amine group, enabling direct functionalization in cross-coupling and C–H amination reactions. This electron-deficient heterocycle delivers high reactivity under palladium catalysis, facilitating efficient access to complex pharmaceutical intermediates. The bromo substituent serves as a reliable handle for further diversification, while the amine moiety enhances solubility and binding affinity in target-directed synthesis.
6-Bromoisoquinolin-3-amine serves as a versatile building block for the synthesis of isoquinoline-based pharmaceuticals and functional materials. The bromine at the 6-position enables palladium-catalyzed cross-coupling reactions, while the primary amine at the 3-position offers a handle for derivatization via acylation, alkylation, or reductive amination. Its bench-stable solid form facilitates handling and purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: