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Structure of 75885-59-5
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2,2-Dimethylcyclopropanecarboxylic acid features a rigid cyclopropane ring with two methyl groups at the geminal position, imparting exceptional steric congestion. This structural constraint enhances stability and influences reactivity in synthetic transformations. The carboxylic acid group enables direct functionalization or coupling reactions, making it a valuable scaffold for medicinal chemistry and materials science applications.
2,2-Dimethylcyclopropanecarboxylic acid serves as a robust building block for strained cyclopropane-containing scaffolds in medicinal chemistry. Its carboxylic acid functionality enables direct derivatization into amides, esters, and acyl chlorides, while the geminal dimethyl substitution enhances stability and modulates lipophilicity. The rigid cyclopropane core imparts conformational constraint, facilitating precise spatial orientation in target molecules. This compound functions effectively in standard coupling reactions and is compatible with diverse protecting group strategies, making it a valuable tool for synthesizing bioactive analogs and complex heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: