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CS-W001157 4
Total: USD 88.00

Pyrimidin-2-yl-methylamine

  • CAS No. 75985-45-4

  • Cat. No. CS-W008578
  • Purity≥95%
  • MDL No.MFCD06212857
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Pyrimidin-2-yl-methylamine|CS-W008578

Structure of 75985-45-4

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Description

Pyrimidin-2-yl-methylamine features a pyrimidine ring linked to a primary amine via a methylene bridge, delivering a versatile scaffold for medicinal chemistry. This bench-stable, moisture-tolerant compound integrates readily into bioactive molecules, serving as a key building block in targeted drug discovery and functional material design.

Application

Pyrimidin-2-yl-methylamine serves as a versatile building block in medicinal chemistry, enabling the construction of pyrimidine-based scaffolds prevalent in kinase inhibitors and antiviral agents. Its primary amine functionality facilitates straightforward derivatization via alkylation, acylation, or coupling reactions. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis and process development workflows.

General Information

  • CAS No. 75985-45-4
  • Cat. No. CS-W008578
  • Purity ≥95%
  • MDL No. MFCD06212857
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃
  • Molecular Weight 109.13
  • Synonym(s) pyrimidinylmethylamine
  • SMILES NCC1=NC=CC=N1

Computational Chemistry Data

  • TPSA   51.8
  • LogP   -0.0647
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group :
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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