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Structure of 76045-71-1
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3-Amino-5-hydroxybenzoic acid features a unique combination of electron-donating amino and hydroxyl groups flanking a carboxylic acid moiety, enabling versatile conjugation in bioactive molecule synthesis. This polar scaffold enhances solubility and facilitates hydrogen bonding in medicinal chemistry applications.
3-Amino-5-hydroxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and peptide-coupled scaffolds. Its ortho-dihydroxy-amino substitution pattern provides multiple handles for derivatization, including amide coupling, electrophilic substitution, and metal-catalyzed cross-coupling. The compound exhibits good bench stability and facilitates purification via standard recrystallization or chromatography, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: