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Structure of 76180-33-1
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2-Fluoro-4-(methylthio)aniline features a fluorinated aromatic ring paired with a methylthio substituent, delivering enhanced electronic and steric properties. This bench-stable intermediate integrates readily into pharmaceutical scaffolds and enables selective functionalization in synthetic routes requiring electron-deficient anilines.
2-Fluoro-4-(methylthio)aniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via Pd-catalyzed cross-coupling and electrophilic substitution reactions. Its methylthio group offers moderate stability and facilitates selective transformations, while the ortho-fluorine supports further functionalization through directed metallation or nucleophilic displacement. The compound exhibits good bench stability and is compatible with standard purification protocols, making it suitable for scalable API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: