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Structure of 762287-58-1
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This boronic acid features a fluorinated aryl moiety paired with a methyl substituent, enabling selective cross-coupling reactivity in palladium-catalyzed transformations. The ortho-fluoro group enhances stability and modulates electronic properties, while the methyl group introduces steric control. Bench-stable and compatible with standard coupling conditions, it facilitates efficient access to substituted biaryl architectures in medicinal chemistry and materials synthesis.
(2-Fluoro-3-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-fluoro and meta-methyl substituents provide predictable regiochemical control and enhanced stability compared to non-fluorinated analogs. The boronic acid functions reliably in diverse synthetic workflows, offering excellent bench stability, straightforward purification, and broad functional group tolerance—making it a practical choice for constructing biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: