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Structure of 76543-27-6
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This 1-[(4-methylphenyl)sulfonyl]-3-azetidinone features a sterically constrained azetidinone core paired with a bench-stable, electron-deficient sulfonyl group. The para-methylphenyl moiety enhances solubility and modulates reactivity, enabling efficient incorporation into synthetic sequences requiring stable β-lactam scaffolds under standard conditions.
1-[(4-Methylphenyl)sulfonyl]-3-azetidinone serves as a stable, bench-ready synthon for β-lactam synthesis, enabling efficient construction of medicinally relevant azetidinone scaffolds. Its sulfonyl group enhances functional group tolerance and facilitates downstream derivatization, while the strained four-membered ring promotes reactivity in nucleophilic addition and ring-opening processes. The compound functions reliably in standard amide coupling and transition-metal-catalyzed transformations, offering predictable behavior in both academic and industrial R&D workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P302+P352
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Lot numbers can be found on the outside label of a product: