Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 869489-04-3
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
(S)-4,4-Difluoropyrrolidine-2-carbonitrile hydrochloride is a stereochemically defined, bench-stable building block featuring a fluorinated pyrrolidine core with a nitrile handle. The electron-deficient difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the protonated amine enables straightforward salt formation for improved solubility. This scaffold integrates efficiently into peptidomimetics and bioactive heterocycles.
(S)-4,4-Difluoropyrrolidine-2-carbonitrile hydrochloride serves as a conformationally constrained, fluorinated building block for medicinal chemistry applications. Its rigid pyrrolidine core enhances metabolic stability and modulates physicochemical properties, while the nitrile group enables diverse downstream transformations. The difluoro substitution at C4 imparts enhanced lipophilicity and bioavailability, making it a valuable scaffold for optimizing kinase inhibitors and CNS-targeted therapeutics. The hydrochloride salt ensures excellent bench stability and ease of handling in standard synthetic workflows.
|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: