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Structure of 767609-14-3
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1-(2,2-Difluoroethyl)piperazine features a fluorinated alkyl chain that enhances metabolic stability and membrane permeability. This electron-deficient moiety integrates readily into bioactive molecules, enabling efficient access to compounds with improved pharmacokinetic profiles in medicinal chemistry applications.
1-(2,2-Difluoroethyl)piperazine serves as a versatile building block in medicinal chemistry, enabling the introduction of a lipophilic, metabolically stable difluoroethyl moiety. Its piperazine core offers multiple sites for functionalization, while the 2,2-difluoroethyl group imparts enhanced membrane permeability and resistance to oxidative metabolism. The compound demonstrates good bench stability and compatibility with standard coupling and derivatization protocols, facilitating efficient synthesis of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501
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Lot numbers can be found on the outside label of a product: