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Structure of 77472-39-0
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(3-Nitrophenyl)methanethiol features a nitro-substituted phenyl ring linked to a thiol group, delivering enhanced reactivity and electron-withdrawing character. This configuration supports efficient conjugation in synthetic transformations and enables selective functionalization in complex molecular architectures. The compound exhibits robust stability under standard conditions, facilitating reliable use in organic synthesis and materials development.
(3-Nitrophenyl)methanethiol serves as a versatile building block for sulfide-based heterocycles and functionalized arylthio compounds. Its ortho-nitro group enhances electrophilicity at the aromatic ring, enabling efficient palladium-catalyzed coupling reactions. The thiol functionality offers reliable conjugation chemistry and facilitates purification via precipitation or ion-exchange chromatography. Bench-stable and compatible with common protecting groups, it functions effectively in multistep synthesis of pharmaceutical intermediates and agrochemical scaffolds.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P405-P501
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Lot numbers can be found on the outside label of a product: