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CS-W001157 4
Total: USD 88.00

Benzenemethanamine, 3,5-dimethoxy-N-methyl-

  • CAS No. 77775-71-4

  • Cat. No. CS-0029514
  • Molecule weight181.23
  • Purity≥97%
  • MDL No.MFCD05864733

*For research and further manufacturing use only, not for direct human use.

Benzenemethanamine, 3,5-dimethoxy-N-methyl-|CS-0029514

Structure of 77775-71-4

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General Information

  • CAS No. 77775-71-4
  • Cat. No. CS-0029514
  • Purity ≥97%
  • MDL No. MFCD05864733
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅NO₂
  • Molecular Weight 181.23
  • Synonym(s) (3,5-diMePh)3PO
  • SMILES CNCC1=CC(OC)=CC(OC)=C1

Description

(3,5-Dimethoxybenzyl)methylamine features a benzyl scaffold with two methoxy groups at the 3- and 5-positions, enhancing electron density and solubility. This amine integrates readily into peptide and small-molecule scaffolds, offering improved metabolic stability and favorable lipophilicity for medicinal chemistry applications.

Application

(3,5-Dimethoxybenzyl)methylamine serves as a versatile building block for bioactive molecule synthesis, enabling efficient access to substituted benzylamines through straightforward functional group manipulation. Its dimethoxy-substituted aromatic core provides enhanced solubility and stability, while the primary amine functionality facilitates coupling reactions, reductive amination, and incorporation into heterocyclic scaffolds common in medicinal chemistry.

Synthesis

  • Route1
    • In-stock
      3,5-Dimethoxybenzaldehyde|CS-W007626
      7311-34-4
    • null|null
      74-89-5
    • ~%
    • In-stock
      Benzenemethanamine, 3,5-dimethoxy-N-methyl-|CS-0029514
      77775-71-4

    References

    • Chemical and Pharmaceutical Bulletin, , vol. 29, # 1 p. 128 - 136

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.49
  • LogP   1.4232
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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