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Structure of 780027-85-2
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1-(2,3,4-Trifluorophenyl)ethanamine features a trifluorinated aromatic ring that enhances electron-withdrawing character and metabolic stability. This amine integrates readily into bioactive scaffolds, offering improved lipophilicity and membrane permeability for medicinal chemistry applications.
1-(2,3,4-Trifluorophenyl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine functionalization. Its trifluorophenyl moiety enhances metabolic stability and modulates lipophilicity, while the primary amine facilitates conjugation in amide couplings, reductive aminations, and electrophilic substitutions. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: