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Structure of 78177-12-5
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6-Isopropylpyridin-2-amine features a sterically hindered isopropyl group at the 6-position, enhancing its stability and solubility in organic media. The pyridin-2-amine core provides a strong nitrogen donor site, enabling efficient coordination in catalytic systems. This compound serves as a robust ligand in transition metal catalysis and functionalizes diverse synthetic intermediates.
6-Isopropylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and direct functionalization. Its ortho-amino group facilitates efficient metal coordination and cyclization reactions, while the isopropyl substituent enhances lipophilicity and metabolic stability. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows, simplifying purification and scale-up.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H301-H310-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: