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CS-W001157 4
Total: USD 88.00

5-(Benzyloxy)-1H-indazole

  • CAS No. 78299-75-9

  • Cat. No. CS-D0863
  • Purity≥97%
  • MDL No.MFCD05664006
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-(Benzyloxy)-1H-indazole|CS-D0863

Structure of 78299-75-9

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Description

5-(Benzyloxy)-1H-indazole features a benzyl ether-linked indazole core, offering enhanced solubility and stability in organic synthesis. This functionalized heterocycle serves as a key intermediate in medicinal chemistry, enabling direct incorporation into bioactive molecules via cross-coupling or derivatization. The benzyloxy group provides orthogonal protection and facilitates downstream transformations.

Application

5-(Benzyloxy)-1H-indazole serves as a versatile building block for the synthesis of bioactive heterocycles, enabling direct functionalization at the indazole core. The benzyloxy group provides orthogonal protection for phenolic oxygen, allowing selective deprotection under mild hydrogenolysis conditions. Its stability under standard reaction protocols facilitates incorporation into diverse medicinal chemistry campaigns and transition-metal-catalyzed coupling sequences.

General Information

  • CAS No. 78299-75-9
  • Cat. No. CS-D0863
  • Purity ≥97%
  • MDL No. MFCD05664006
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂N₂O
  • Molecular Weight 224.26
  • Synonym(s) oxy)-1H-indazoL
  • SMILES C1(OCC2=CC=CC=C2)=CC=C(NN=C3)C3=C1

Computational Chemistry Data

  • TPSA   37.91
  • LogP   3.1419
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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