(R)-2-Amino-1,1-diphenylpropan-1-ol

Name: (R)-2-Amino-1,1-diphenylpropan-1-ol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 78603-93-7
Cat. No. CS-0158215
Purity≥97%
MDL No.MFCD02677967

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Amino-1,1-diphenylpropan-1-ol|CS-0158215

Structure of 78603-93-7

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Description

(R)-2-Amino-1,1-diphenylpropan-1-ol features a chiral center flanked by two phenyl groups and a primary amine, delivering high stereochemical fidelity in asymmetric synthesis. This bench-stable, moisture-tolerant scaffold integrates readily into catalytic systems and serves as a key building block for bioactive molecule construction.

Application

(R)-2-Amino-1,1-diphenylpropan-1-ol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of pharmaceutically relevant scaffolds. Its tertiary alcohol and amino functionalities provide orthogonal handles for selective derivatization, while the sterically congested quaternary center enhances metabolic stability. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling and reduction protocols.

General Information

CAS No. 78603-93-7
Cat. No. CS-0158215
Purity ≥97%
MDL No. MFCD02677967
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₁₇NO
Molecular Weight 227.30
Synonym(s) (R)-2-Amino-1,2-Diphenyl-1-Propanol
SMILES C[C@H](C(C1=CC=CC=C1)(C2=CC=CC=C2)O)N

Computational Chemistry Data

TPSA 46.25
LogP 2.2697
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-Amino-1,1-diphenylpropan-1-ol

CAS No. 78603-93-7

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