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Structure of 791642-68-7
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5-Bromo-2-iodoanisole features a strategically positioned bromo and iodo substituent on an aromatic ring, enabling selective cross-coupling reactions. The methoxy group enhances solubility and directs regiochemistry, while the halogen pairs offer orthogonal reactivity for sequential transformations in complex molecule assembly.
5-Bromo-2-iodoanisole serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The bromo and iodo substituents offer orthogonal reactivity in sequential coupling processes, while the methoxy group provides electronic modulation and enhanced solubility. Bench-stable and readily purified by flash chromatography, it functions reliably in Suzuki, Stille, and Negishi couplings, supporting scalable synthesis of functionalized heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: