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Structure of 79387-69-2
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5-Iodopyrimidin-2(1H)-one features a reactive iodine atom at the 5-position paired with a pyrimidinone core, enabling efficient cross-coupling transformations. This bench-stable heterocycle integrates readily into diverse molecular architectures, serving as a key intermediate in medicinal chemistry and materials science applications.
5-Iodopyrimidin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the efficient construction of substituted pyrimidine scaffolds. Its iodine substituent facilitates reliable C–C and C–heteroatom bond formation under standard conditions, while the pyrimidinone core provides excellent functional group tolerance and bench stability, making it ideal for modular synthesis of bioactive molecules and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: